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Scientist, Department of Biology

Company: EvolveImmune Therapeutics
Location: Hartford
Posted on: March 26, 2020

Job Description:

Who We Are:EvolveImmune Therapeutics is a next-generation immunotherapy platform company based in Farmington, CT.--Building upon research that originates from the Sidi Chen Lab at Yale University, EvolveImmune is leveraging a novel in vivo target discovery platform to develop a broad portfolio of first-in-class molecules for unmet needs in oncology and immune diseases.The RoleWe are looking for a talented scientist to join the department of biology. In this role, the candidate will contribute towards experiments designed for target validation and lead candidate selection. This is an exciting opportunity for someone who is excited about discovering the role of less studied genes in cancer immunology and more broadly human immunology and is driven by development of therapeutics. We are looking for candidates who enjoy working in a team and can leverage the growth opportunities that a matrixed environment provides. In addition, it is desired that the candidates have excellent communication skills. ResponsibilitiesDesign and conduct in-vitro experiments using mouse or human primary immune cells for validation of lead targets.Design and conduct in-vitro experiments to test hypotheses regarding the immunomodulatory roles of lead targets.Design and conduct experiments that will support the development of antibodies against the lead targets and contribute towards lead candidate selection.Provide support for in vivo studies in form of flow cytometry, cytokine measurements and drug concentration measurements.Keep records of experiments in electronic notebooks, analyze data and prepare presentation ready graphs.QualificationsPhD in immunology or a related field with 0-3 years of postdoctoral or industry experienceExperience with isolation and purification of immune cells from human peripheral blood cells and/or mouse tissuesExpertise in assays testing for immune cell function in vitro (eg. TCR stimulation assays, cytotoxicity assays, B cell proliferation assays and assays to test for function of other immune cells such as NK cells and Neutrophils)Expertise in multi-color flow cytometryExperience with multiplex ELISA systems.Expertise in use of data analysis software such as Flowjo, Excel and Prism as well as knowledge of statistical methods and curve fitting.EvolveImmune will provide a competitive compensation package based on the level of the experience of the candidate.

Keywords: EvolveImmune Therapeutics, Hartford , Scientist, Department of Biology, Other , Hartford, Connecticut

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