Sr Scientist, Protein Biochemistry

Company: Regeneron Pharmaceuticals, Inc.
Location: Tarrytown
Posted on: July 18, 2025

Job Description:

Regeneron is seeking a highly motivated and passionate Senior Scientist to join our Protein Biochemistry team. In this exciting role, you will play a critical part in implementing innovative biophysical assessment strategies to support a wide range of drug candidate modalities. This position will also provide matrix based support for the characterization of novel modalities such as gene therapy agents and oligonucleotides as well as complex therapeutic strategies and approaches. A Typical Day Might Include: Design, develop, and execute biophysical assays supporting developability assessment at different stages of lead characterization. Understand current computational biophysics approaches (workflows, software) for in silico modeling of surface properties of antibody-like molecules for in silico profiling. Serve as a representative of our department on cross-functional teams with accountability for biophysical characterization. Contribute results & analysis for protein or new modality characterization to provide molecular profiles and developability assessments of therapeutic assets, that support the pipeline, in a timely manner and aligned with partner functions Recommending, adapting and developing analytical methods for protein characterization Review the literature and works with their team to design experiments that solve biophysical problems for key partners. Supervise and support scientists with critical data review as well as career development. This Role Might Be for You If You : Have familiarity with biologics development and novel biophysical approaches to drive innovationAre hardworking, efficient, flexible, and able to perform key responsibilities in a fast-paced, team environment Have the ability and passion for independently learning new methods and software Possess excellent written and verbal communication skills and the ability to prepare slides and author reports and manuscripts for internal and external presentations, communicating biophysical results to both technical and general audiences. To be considered for this opportunity, you must have the following: Ph.D. , MS or BS or equivalent degree in biophysics, pharmaceutical sciences, biochemistry, chemical engineering or related field with PhD, 0-3, MS 8, BS 10 years proven experience in characterization of therapeutic protein candidates. Experience developing and troubleshooting analytical methods. Experience with statistical and experimental design, molecular modeling, graphing and mathematical analysis softwares is a plus. In-depth knowledge of and demonstrated expertise operating biophysical and biochemical techniques such as Light Scattering, Analytical Chromatography (SEC, HIC, IEX), Differential Scanning Fluorescence and/or Differential Scanning Calorimetry, Raman, ROA, and/or FTIR spectroscopy, Analytical Ultracentrifugation, Bilayer Interferometry, and Electrospray Mass Spectrometry. In-silico modeling skills are a bonus. Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits, which often include (depending on location) health and wellness programs, fitness centers, equity awards, annual bonuses, and paid time off for eligible employees at all levels! Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business. For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location. Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc. Salary Range (annually) $108,300.00 - $176,700.00

Keywords: Regeneron Pharmaceuticals, Inc., Hartford , Sr Scientist, Protein Biochemistry, Science, Research & Development , Tarrytown, Connecticut