Research Scientist
Company: Takeda
Location: Boston
Posted on: January 12, 2026
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Job Description:
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job opportunity: JOB LOCATION: Cambridge, MA POSITION : Research
Scientist POSITION DESCRIPTION : Takeda Development Center
Americas, Inc. is seeking a Research Scientist with the following
duties: Contribute to discovery projects by independently designing
and developing well-defined mechanistic experiments and projects
within oncology immunotherapy research focusing on leveraging Vd1
T-cells as cancer treatment. Lead from the lab to advance novel and
differentiated products toward clinical milestones, by working
collaboratively with internal cross-functional teams and external
partners. Design, execute, and interpret functional in vitro, and
ex vivo assays to understand the therapeutic mechanism-of-action
and play an active role in subsequent scientific discussions to
drive decisions around Vd1 T-cells as possible cancer therapy.
Propose novel projects based on internal results, external
partners, and published reports and demonstrate leadership through
effective communication of study plans/value, and research results.
Actively participate with the team to help isolate VD1 cells from
blood. Tutor less experienced operators in complex procedures such
as large scale Vd1 isolation from blood. Use immune cell
characterization and function assessments, such as multi-color flow
immunophenotyping, multiplex cytokine measurement, cytotoxicity
assay, and other molecular based assays and cell-based
functionality assays. Contribute to evaluation of novel engagers
for Vd1 T-cells in in vitro and ex vivo model systems. Contribute
to development of new assays and strategies to determine Vd1
T-cells functionality and biology to improve the efficiency of
tumor control of Vd1 T-cells in presence of Cell Engagers.
Collaborate with other departments to meet deadlines and generate
data crucial for the programs in execution. Contribute to the
writing of relevant research reports to be included in regulatory
filings. Prepare and present comprehensive technical or project
reports and formal presentations and posters to full range of
internal/external audiences. Maintain laboratory notebooks and keep
in compliance with Takeda policies; up to 20% remote work allowed.
REQUIREMENTS: PhD degree in Biology, Cancer Studies, or related
field plus 3 years related experience. Prior experience must
include: Isolate, culture and expand Vd1 gamma delta T cells;
Design and execute in vitro/ex vivo assays of Vd1 cell function,
including cytotoxicity, survival, and proliferation; Analyze
experimental data and determine the relevance of results based on
background knowledge of Vd1 gamma delta cell biology; Contribute to
evaluation of novel immunotherapy products based on Vd1 gamma delta
cell biology; Experience with gene engineering of Vd1 cells. Full
time. $118,800.00 – $191,600.00 per year. Competitive compensation
and benefits. Qualified applicants can apply at
https://jobs.takeda.com . Please reference job R0171383. EOE Any
individual may provide documentary evidence bearing on this
application, with information on available workers and information
on wages and working conditions, to the Certifying Officer, U.S.
Department of Labor, Employment and Training Administration, Office
of Foreign Labor Certification, 200 Constitution Avenue, NW, Room
N-5311, Washington, DC 20210. Locations Boston, MA Worker Type
Employee Worker Sub-Type Regular Time Type Full time
Keywords: Takeda, Hartford , Research Scientist, Science, Research & Development , Boston, Connecticut